Respiratory pathogens in infants less than two months old hospitalized with acute respiratory infection

نویسندگان

چکیده

Lower acute respiratory infections (ARI) are a frequent cause of morbidity and mortality in infants, viruses being the major causative agents. The aim this work was to determine pathogen frequency, clinical characteristics outcome infants <2 months old hospitalized with ARI. A retrospective study performed during five-year period (2008–2011, 2014–2016). Respiratory atypical bacteria were studied using FilmArray-Respiratory Panel. Demographic characteristics, hospitalization course outcomes evaluated. Of 137 ARI studied, 94.9% positivity rate as determined 117 community-acquired infection 20.0% 20 who acquired their birth neonatal intensive care units (NICU) (nosocomial ARI) ( p < 0.001). In infection, syncytial virus (RSV) (52.1%) Rhinovirus/Enterovirus (RV/EV) (41.0%) most detected pathogens. Coinfections one quarter RSV-RV/EV combination. nosocomial RV/EV, RSV or Parainfluenza-3 single Most presented lower (81.2%) while NICU had upper (55.0%). median length stay (LOS) 4 days (IQR: 2–6). Positive longer LOS (71 [IQR:42–99]) compared negative (58 [IQR: 49–71]) = 0.507). agents <2-months old, RV/EV frequently detected. Although low observed they may prolong LOS. Las infecciones respiratorias agudas (IRA) son una causa habitual de morbimortalidad en infantes y los respiratorios agentes causales más frecuentes. El objetivo este trabajo fue determinar la frecuencia patógenos respiratorios, sus características evolución clínica menores dos meses internados por IRA. Se realizó un estudio retrospectivo que comprendió 5 años (2008-2011, 2014-2016). estudiaron las bacterias atípicas utilizando el panel respiratorio FilmArray. evaluaron demográficas clínicas, así como durante internación. En IRA se determinó positividad del 94,9% lactantes con infección adquirida comunidad (IRA-C) 20,0% adquirieron su hospitalización unidad cuidados intensivos (IRA-N) 0,001). IRA-C frecuentes fueron sincicial (52,1%) rinovirus/enterovirus (41,0%). determinaron coinfecciones cuarto infantes, combinación frecuente. IRA-N detectó o parainfluenza-3 únicos patógenos. La mayoría presentaron baja (81,2%), mientras mitad UCIN tenían alta (55,0%). mediana duración internación días (RIC: 2-6). Los positivos tuvieron larga [RIC: 42-99]) comparación negativos 49-71]) 0,507). principales requirieron internación; RV/EV. Aunque observó tasa nosocomial, estos podrían prolongar

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ژورنال

عنوان ژورنال: Revista Argentina De Microbiologia

سال: 2021

ISSN: ['1851-7617', '0325-7541']

DOI: https://doi.org/10.1016/j.ram.2020.05.001